Genetic Epidemiology in Aging Research
نویسندگان
چکیده
منابع مشابه
Genotyping Informatics and Quality Control for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort.
The Kaiser Permanente (KP) Research Program on Genes, Environment and Health (RPGEH), in collaboration with the University of California-San Francisco, undertook genome-wide genotyping of >100,000 subjects that constitute the Genetic Epidemiology Research on Adult Health and Aging (GERA) cohort. The project, which generated >70 billion genotypes, represents the first large-scale use of the Affy...
متن کاملEpidemiology of aging.
The last quarter of the 20th century has seen the formal coming of age of the study of the health, diseases, and disabilities of older adults, as well as of aging itself. Epidemiologic research on aging developed out of groundbreaking gerontologic studies that have been carried out since the 1940s, the establishment of the National Institute on Aging in 1974 (an outgrowth itself of the first Wh...
متن کاملEpidemiology of aging.
Over the past century, truly remarkable changes have been observed in the health of older persons throughout the world, and these changes have strongly impacted society. The growth of the older population has resulted mostly from a general increase in the overall population size but is also strongly influenced by major declines in leading causes of mortality. These demographic transformations r...
متن کاملCharacterizing Race/Ethnicity and Genetic Ancestry for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort.
Using genome-wide genotypes, we characterized the genetic structure of 103,006 participants in the Kaiser Permanente Northern California multi-ethnic Genetic Epidemiology Research on Adult Health and Aging Cohort and analyzed the relationship to self-reported race/ethnicity. Participants endorsed any of 23 race/ethnicity/nationality categories, which were collapsed into seven major race/ethnici...
متن کاملResearch Methods in Epidemiology.
Epidemiology is the study of the distribution and determinants of health-related states and in specified populations and the application to control health problems. Classified as either descriptive or analytical, a variety of epidemiologic approaches can be used to allow assessment of hypothesized risk factor exposure with disease outcomes. This article reviews salient aspects of epidemiologic ...
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ژورنال
عنوان ژورنال: The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
سال: 2009
ISSN: 1079-5006,1758-535X
DOI: 10.1093/gerona/gln021